At the least 2-4 weeks exposure is required to establish exhaustion. Another factor capable of induce exhaustion are inhibitory receptors together with programmed cell demise protein 1 (PD1), CTLA-4, T cell membrane protein-3 (TIM3), and lymphocyte activation gene three protein (LAG3). Soluble molecules comparable to cytokines IL-10 or TGF-β are also in a position to […]